About Me


Ph.D., 2012, Bioinformatics, Georgia Institute of Technology

B.S., 2007, Control Science and Engineering, Tsinghua University


Academic Appointments

Assistant Professor, 2017, Michigan State University

Postdoctoral Associate, 2016, Stanford University

Postdoctoral Associate, 2012-2016, Massachusetts Institute of Technology and Broad Institute


Research Interests

Four major computational biology research topics include:

Probabilistic modeling of long-range three-dimensional enhancer-gene networks in diverse cellular-contexts and inference of hierarchical regulatory logic of combinatorial transcription factors on gene expression.

• Network-based prediction and functional annotation of non-coding genetic variants associated with complex phenotypes in different species.

• Machine learning algorithms to predict regulatory elements of gene expression (insulators, enhancers and boundary elements), large-scale chromatin domains, and histone modification signatures (‘histone-code’) based on genomics, epigenomics and transcriptomics data.

• Statistical and computational methodology development for efficient design, analysis and interpretation of biological big-data generated from new high-throughput techniques.