The Department of Computational Mathematics, Science and Engineering (CMSE) is unique among computational academic units nationally; it is the first to comprehensively treat computation as the "triple junction" of algorithm development and analysis, high performance computing, and applications to scientific and engineering modeling and data science. This approach recognizes computation as a new discipline rather than being decentralized into isolated sub-disciplines. CMSE, jointly administered by the College of Natural Science and the College of Engineering, will enable application-driven computational modeling (“pull”), while also exposing disciplinary computational scientists to advanced tools and techniques (“push”), which will ignite new transformational connections in research and education.